WebOct 26, 2016 · Researchers have identified a gene (CYFIP2) associated with binge eating. This finding represents one of the first examples of a genome-wide significant genetic factor to be identified for binge ... WebCYFIP2, encoding the evolutionary highly conserved cytoplasmic FMRP interacting protein 2, has previously been proposed as a candidate gene for intellectual disability and autism because of its important role linking FMRP-dependent transcription regulation and actin polymerization via the WAVE regulatory complex (WRC).Recently, de novo variants …
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WebБәхәс:CYFIP2. Бәхәс. : CYFIP2. Бу мәкалә тематикасы «Биология» википроекты белән бәйле. Аның максаты — темалары буенча Биология белән бәйле мәкаләләрне төзү һәм яхшырту. Теләсәгез, мәкалә өстендә ... WebAug 13, 2024 · Variants of the cytoplasmic FMR1-interacting protein 2 (CYFIP2) gene are associated with early-onset epileptic encephalopathy, intellectual disability, and developmental delay.However, the current understanding of the molecular functions of CYFIP2 is limited to those related to actin dynamics, and thus, the detailed mechanisms … how do i backup whatsapp messages
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WebOct 29, 2024 · The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its critical role in proper neuronal development and function. CYFIP2 is involved in regulating cellular actin dynamics and also interacts with RNA-binding … WebJan 9, 2024 · Cyfip2 was expressed highly in cortex, striatum, and hippocampus of wildtype mouse brain, and loss of 1 allele caused a layer-specific Cyfip2 decrease and F-actin (see 102610) increase in the medial prefrontal cortex (mPFC) of adult Cyfip2 +/- mice. F-actin is the key cytoskeletal component of excitatory synapses, and consequently, the F-actin ... WebCYFIP2 is sufficient for caspase activation and cellular apoptosis, reminiscent of p53 activation. Together, these results suggest that CYFIP2 is a direct p53 target gene that may be part of a redundant network of genes responsible for p53-dependent apoptosis. In addition, the sensitivity of CYFIP2 protein subcellular localization to Leptomycin ... how much is labor for tile installation