WebDec 1, 2016 · To visualize the phase separation of DAXX in live cells, we developed an ''Opto-DAXX'' protein model by fusing DAXX with mCherry and a CRY2 domain, the latter being the photolyase homology region ... WebSep 15, 2024 · Here we report CRY2-CIB1 and CRY2-CRY2 interactions are governed by well-separated protein interfaces at the two termini of CRY2. N-terminal charges are …
CRY2/CRY2 OptoBase
WebSep 15, 2024 · Here we show that phase separation of UTX underlies its chromatin-regulatory activity in tumour suppression. A core intrinsically disordered region (cIDR) of UTX forms phase-separated liquid ... WebJan 1, 2024 · We speculated that intracellular phase separation could arise from an increased self-association affinity of Cry2 upon blue light activation, which would represent a controllable change to the effective valency of the constructs, resulting in the crossing of a phase boundary above a saturation concentration. skittles commercial 2021
Phase separation of 53BP1 determines liquid-like
WebJan 12, 2024 · We speculated that intracellular phase separation could arise from an increased self-association affinity of Cry2 upon blue light activation, which would … WebNov 23, 2024 · For the Cry2 plasmids, WNK1 fragments were generated by PCR or as synthetic gBlocks and were ligated via restriction cloning to the XmaI site of linearized Cry2PHR or Cry2Olig ... The screeners scored the degree of phase separation (no phase separation, nucleation, and spinodal decomposition) for each numbered cell. ... WebPhase separation of 53BP1 determines liquid-like behavior of DNA repair compartments. EMBO J, 2024 LADL: light-activated dynamic looping for endogenous gene expression control. ... Optogenetic protein clustering … skittles commercial with bride and groom