WebMar 23, 2024 · For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10-20% of all cancer patients. Although nephrotoxicity associated with platinum-based agents is well recognized, treatment of cisplatin-induced acute kidney injury is mainly su … WebPlatinum compounds, such as carboplatin and cisplatin, are commonly used for the treatment of endometrial, ovarian and testicular cancer. Conflicting studies have been reported with regards to the sensitivity of MMR deficient tumors cells to platinum treatment.
Cisplatin nephrotoxicity - UpToDate
WebJun 6, 2024 · Cisplatin-based concurrent chemoradiotherapy has been identified as the primary and standard treatment for locally advanced nasopharyngeal carcinoma (NPC). However, the side effects of cisplatin affect the compliance to therapy. Thus, the search for a platinum-based substitute for NPC has always been a research focus. WebOct 13, 2024 · Platinum-based chemotherapy, including cisplatin, carboplatin, and oxaliplatin, is prescribed to 10-20% of all cancer patients. Unfortunately, platinum resistance develops in a significant... homemade pantry moth traps
Cisplatin: Uses, Interactions, Mechanism of Action - DrugBank
WebPlatinum-based anticancer drugs, such as cisplatin, are standard chemotherapeutic agents in ovarian cancer therapy. Citation 39 , Citation 40 This class of drugs can penetrate the nucleus of cancer cells and form adducts with genomic or mitochondrial DNA to block the production of DNA, mRNA, and proteins, arrest DNA replication, and activate ... WebSep 1, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is a white to light yellow lyophilized powder. Each vial of Cisplatin for injection, USP … WebCisplatin was administered as the initial platinum-based treatment in 149 patients (67%) in the cetuximab group and in 135 patients (61%) in the chemotherapy-alone group. homemade paper folding machine